Involvement from the Limbic System to Spasmodic Dysphonia

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Brainstem pathology in spasmodic dysphonia.

Spasmodic dysphonia (SD) is a primary focal dystonia of unknown pathophysiology, characterized by involuntary spasms in the laryngeal muscles during speech production. We examined two rare cases of postmortem brainstem tissue from SD patients compared to four controls. In the SD patients, small clusters of inflammation were found in the reticular formation surrounding solitary tract, spinal tri...

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Spasmodic dysphonia, a form of the neurologic condition known as dystonia, results from involuntary spasms of the larynx, producing interruptions of speech and changes in voice quality. The pathogenesis of spasmodic dysphonia is not well understood. However, several genetic mutations have been identified that cause different forms of dystonia. In some individuals, these genetic mutations result...

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ژورنال

عنوان ژورنال: Koutou (THE LARYNX JAPAN)

سال: 2020

ISSN: 0915-6127,2185-4696

DOI: 10.5426/larynx.32.115